This run is 21 keys + Love and Origami. I think it takes around 50 mins if I take the time to do all the kill missions.
I'd love to hear any ideas for improvement.
start at the Kaidan teleport point
pickup TEXTS from phone
activate tracer and find 1st signal for TEXTS at 318 605
run to diner start LOVE and ORIGAMI
use book and note
start HELL'S ARSENAL from hell device
examine hell device
teleport to bathhouse
run S to 260 687 and find 2nd signal for TEXTS, make sure scanner is active for this step
run inside bathhouse and start CHASING BAD LUCK at 188 810
enter oni camps through door at 240 811, find and kill fuun and destroy 5 weapon caches
note fuun teleports around the outside of the area, also can appear behind the little building with the energy barrier on the door
run N to 43 1018 and start MASK OF THE ONI
pickup mask
teleport to bathhouse, run inside turn in mask at 172 798
leave bathhoue, run straight E to 3rd signal for TEXTS at 390 795
run E then N around building to 471 901, examine letter for LOVE AND ORIGAMI
teleport to ginpachi park, run around tree to 947 733, examine letter for LOVE AND ORIGAMI
teleport to diner, run to 370 605 and start FEED THE TANK
run to 4th signal in alley at 501 604
run to fallen jingu clan at 550 588, start quest and defeat ambush and pickup katana
run N, get tank battery at 569 687
run N then E, get tank battery at 638 800
run W to pachinko parlor and examine origami at 453 812 for LOVE AND ORIGAMI
teleport to CDC camp, climb rubble to the N then start DEATH AND NOODLES at crumpled instructions 900 424
head NE into CDC camp and collect 3 supplies
run back to 887 419 and go through breach
run to tank at 791 474 and get battery
teleport to diner, hand in katana and supplies
teleport to bathhouse
run inside bathhouse and examine origami at 179 789 for LOVE AND ORIGAMI
it's the one on the bench in the corner
start SAMURAI ROBOTS and THE GHOST LORD at 188 810
teleport to diner
run S, get tank battery at 282 501
run S, get tank battery at 247 446
run W, kill Tsuwamono at 145 422
teleport to the wall or run east along quarantine walls
get tank battery at 406 423
teleport to diner, run to tank at 373 605 and turn in FEED THE TANK
teleport to dream palace, climb ladder at 619 672, start CORPSE AND THE KEY on roof
pickup key
jump off building towards SE, enter dream palace to complete CORPSE AND THE KEY
run east and kill the daimyo
this ends the northern part, you should have 10 keys so far
teleport to the wall
head S to the friendly robot, then jump down and follow traintracks E to stairway at 540 322
climb stairways to top and start SHORT CIRCUIT at suspicious cyborg
pickup robot pieces to complete quest
run E to 711 322 and start HARDWARE TEST
run E to images at 783 338 start WASTE NOT
examine images
head back W and go up ramp to to 709 391, start JUDAS MECH at damaged cyborg arm
kill drones on way to 600 408, target and then kill mech there
note if the mech was too damaged by npcs, you won't get credit and will have to wait for respawn
if you haven't completed HARDWARE TEST, kill drones in area
run to tagging rifle at 535 412, start TENEBROUS SKY
keep looking up and shoot birds whenever possible
teleport to CDC camp
climb rubble to the N and open crate at 940 375
cross bridge at 894 363 and run to 912 273 start MIDDLE MANAGMENT at drone
inspect orders
follow road S to 898 196, inspect corpse
follow streets to the playground near Jung at 824 175
if you havent finished TENEBROUS SKY, shoot birds from the playground
kill Giichi at 792 183
run S and follow streets to door at 792 126
use door, defeat ambush
use door, kill ghost
follow street SE to 864 82, start MESSAGE TO HELL from oni corpose
go SE around wall and complete quest
run to 853 20 and open crate
head W to bridge at 715 80
follow bridge/road N to 727 233, start PIRATING THE SIGNAL at scanner
pick up scanner and activate
head S a bit then follow road E to gnawed cadaver at 780 235, start RAVENOUS
follow tracks, kill target
activate scanner and goto 829 257 for 1st transmitter
teleport to shinto shrine and run to 747 132 for 2nd transmitter
follow roads E then N to 873 156 and use transmitter to complete PIRATING THE SIGNAL
note you can do this from the west side of the brick wall
teleport to the wall, run S down ramp, jump off to west at 381 389
run W a bit and start THE FRUITING BODIES at orochi orders
run S and then E around shipping containers to crate at 376 250, open to complete WASTE NOT
complete ape quest before getting on the boat
kill stuff on the way and work your way to sea captain's hat at 476 99
start O CAPTAIN and climb onto boat
note there are more mobs for FRUITING BODIES on the boat
head E to back of boat and climb ladder at 530 77
climb 2 sets of stairways
climb ladder at 519 71 to very top of ship, kill captain
